J. H. Miller to H. R. Miller (14 November 1862)

Describes the conditions in Pontotoc and surrounding areas following the Battle of Corinth; the ease following the Confederate Army\u27s settling in Holly Springs; crops; sickness among his slaves; the building of nearby fortifications and rumors of movementhttps://egrove.olemiss.edu/ciwar_corresp/1585/thumbnail.jp

Book Reviews

Book reviews by Joseph J. Miller, William J. Syring, Richard F. Swisher, Ronald P. Rejent, James H. Graham, Jr., Daniel C. O\u27Grady, Theodore Stensland, James H. Neu, and Lawrence J. Petroshius

Recollections of My Research in Developing the Heart-Lung Machine at Jefferson Medical College

A personal memoir written by Dr. Bernard J. Miller about his introduction to and interest in medical research as well as his experiences working on the heart-lung machine. He focuses specifically on his working relationship with John H. Gibbon, Jr., the development of a viable oxygenator and ventilator, and early testing of the machine on animal

Discussion of Recent Decisions

Notes by G. Kloek, J. R. Scott, B. P. Morissette, R. L. Tindall, G. W. McGurn, W. J. Davis, E. B. Miller, G. O. Hebel, H. H. Simpson Jr., B. G. Ottenhof

Discussion of Recent Decisions

Notes by G. Kloek, J. R. Scott, B. P. Morissette, R. L. Tindall, G. W. McGurn, W. J. Davis, E. B. Miller, G. O. Hebel, H. H. Simpson Jr., B. G. Ottenhof

J. H. Miller, Jr. to H. R. Miller (27 July 1862)

Describes his feeling during recent retreat, preparing for an upcoming march rumored as heading either Chattanooga or Savannah, destruction in his father\u27s town and knowledge they will pass through Mobile.https://egrove.olemiss.edu/ciwar_corresp/1577/thumbnail.jp

Studies relating to the breast, its tumours and fluids

This thesis comprises 61 papers which describe work undertaken between 1972 and 1985. The research was performed in order to obtain basic information on the environment and the biochemical processes existing within the female breast. It was thereby hoped to achieve a better understanding of events which occur during the development of breast disease, particularly breast cancer.Hormones are involved not only in the natural development of normal breast but also in the aetiology of many breast abnormalities and, most importantly, in the continued growth of a proportion of breast cancers. A major aspect of the research described in this thesis is concerned with the measurement of steroid hormones, their metabolism and receptors in the breast, its tumours and secretions. Additionally studies have been performed to assess the significance of other markers of tumour behaviour and to determine whether agents such as LHRH analogues have direct effects within the breast.The potential of the breast to modify its own hormonal environment has been investigated by performing in vitro incubations with steroid precursors. Pathways leading to both active androgens and oestrogens have been identified. Biosynthesis of 5 reduced androgens occurs in all types of breast tissue but is particularly associated with apocrine differentiation. The production of oestrogen or "aromatization" was detected in a proportion of breast cancers but not in non-malignant tissue. The significance of tumour aromatase is controversial but it may be important in oestrogen-dependent cancers growing in post-menopausal women who have low circulating levels of oestrogen.In order to estimate levels of androgen precursors within the breast, measurements of DHA sulphate have been made in breast secretions obtained by nipple aspiration and breast cyst fluids. Remarkably high, but variable, concentrations have been detected. Further investigations of the composition of such breast fluids have shown them to have a distinctive composition in terms of ionic content, major types of immunoglobulins and concentrations of plasma-, platelet-associated and other proteins. Cyst fluids may be subdivided into two major populations which are lined by different epithelium and have a differing natural history.Several series of breast cancers have been analysed for either androgen receptors, progestogen receptors, cyclic AMP binding proteins, prostaglandins or expression of lectin binding. These have been suggested to be markers of metastatic potential or hormone-responsiveness. Inter-relationships have been made with oestrogen receptors and other tumour/patient characteristics but assessment of clinical value awaits patient follow-up.The possibility that polypeptide hormones have direct actions on the breast was investigated by culturing breast cancer cells with LHRH and its analogues. Marked inhibitory effects which appear to be mediated by a specific recognition mechanism have been demonstrated. These findings are reviewed in terms of their significance to the management of patients with breast disease.SECTION A STEROID METABOLISM BV THE HUMAN BREAST AND ITS TUMOURS 1. Miller W R, McDonald D, Forrest A P M and Shivas A A (1 973) Metabolism of androgens by human breast tissue. The Lancet i; 912-913. 2. Miller W R, McDonald D and Forrest A P M (1 973) Steroidogenesis in human breast cancer, benign breast disease and normal breast tissue. Biochemical Society Transactions l;762-765. 3. Miller W R, McDonald D, MacFadyen I, Roberts M M and Forrest A P M (1974) Androgen metabolism in gynaecomastic breast tissue. Clinical Endocrinology 3.; 123-130. 4. Miller W R and Forrest A P M (1974) Oestradiol synthesis by a human breast carcinoma. The Lancet ii:866-868. 5. Miller W R and Forrest A P M (1 976) Oestradiol synthesis from C.|q steroids by human breast cancers. Br J Cancer 33.; 116-118. 6. Miller ¥ R, Shivas A A and Forrest A P M (1978) Factors affecting testosterone metabolism by human breast tissues. Clinical Oncology l;77-85. 7. Miller W R (1981) Inhibition of aromatization by aminoglutethimide in breast cancers - clinical relevance. In "Aminoglutethimide. An alternative endocrine therapy for breast carcinoma" ed. R W Elsdon-Dew, I M Jackson and G F B Birdwood. Royal Society of Medicine International Congress and Symposium Series No. 53. Academic Press Inc (London) Ltd. 8. Miller W R, Hawkins R A and Forrest A P M (1981) Steroid metabolism and oestrogen receptors in human breast carcinomas. Europ J Cancer (Clin Oncology) 17:913-917. 9. Mason R C, Burns D A, Miller W R, Hawkins R A and Forrest A P M (1981) Tumour steroid synthesis and oestrogen receptor status in breast cancer patients. Breast Cancer Treatment & Research l;263-266. 10. Miller W R, Hawkins R A and Forrest A P M (1 982) Significance of aromatase activity in human breast cancer. Cancer Research 42:3365-3368. 11. Miller W R Aromatase activity and breast cancer. Turkey National Cancer Prevention Association Booklet. 12. Miller W R and Forrest A P M (1 978) In vitro effects of oestradiol on testosterone metabolism by human breast cancers. European J Cancer 14:865-867. 13. Mason R C, Miller W R, Hawkins R A, Brown M S and Forrest A P M (1983) Effects of drugs associated with hyperprolactinaemia and plasma steroids and on steroid receptors and metabolism in human breast cancer. Breast Cancer Research and Treatment 3;331-338. 14. Miller W R, Telford J, Dixon J M and Shivas A A (1985) Androgen metabolism and apocrine differentiation in human breast cancer. Breast Cancer: Research and Treatment 3; 67- 73. 15. Miller W R (1986) Steroid metabolism in breast cancer. In "Breast cancer: Treatment and Progress" Ed. B A Stoll. Published Blackwell Scientific Publications, pp.156-172 16. MillerW R (1986) Steroid metabolism in breast cancer. Reviews on Endocrine-Related Cancer. 23;23-30.SECTION B. STEROID METABOLISM BY (A) RAT MAMMARY TUMOURS AND (B) OTHER HUMAN TISSUES 17. Miller W R, Forrest A P M and Hamilton T (1974) Steroid metabolism by human breast and rat mammary carcinoma. Steroids 235379-395. 18. Miller W R (1976) Hyperprolactinaemia and steroid metabolism by rat mammary adenocarcinoma. Cancer Research 36.5336-338. 19. Miller W R, Buchan R and Forrest A P M (1974) Effects of prolactin upon C₁₉ steroid metabolism by rat mammary carcinoma. Biochemical Society Transactions 2.5312-314, 20. Buchan P, Fraser A T and Miller W R (1976) The effect of perphenazine treatment on testosterone metabolism by established rat mammary carcoinomas. Biochem Soc Transact A; 1100-1102. 21. Buchan P and Miller W R (1978) Perphenazine and testosterone metabolism by mammary tumours in oophorectomised rats. Biochem Soc Transact 6;133-134. 22. Miller W R (1976) Hormone status and testosterone metabolism of DMBA induced rat mammary carcinomas. Br J Cancer 34:296- 298 23. Miller W R (1976) In vitro effects of oestrogen on 5α reduction of testosterone in hormone dependent rat mammary carcinomata. Br J Cancer 33:474-477. 24. Miller W R (1976) in vitro effects of prolactin upon testosterone metabolism by rat mammary carcinomas. European J Cancer 18:679-682. 25. Miller W R and Telford J (1 975) The effect of oestrogen on steroid metabolism by rat mammary carcinomas. Bui Soc Int Chir 3A;531-533. 26. Miller W R (1980) The effects of serial passage on the endocrine response and steroid metabolism of a rat transplantable mammary carcinoma. Br J Cancer J(2.;326-330. 27. Miller W R, Stewart R and Hawkins R A (1979) Hormonal status and steroid metabolism in two transplantable rat mammary tumours. Br J Cancer 29.;200-204. 28. Miller W R, Shivas A A and Forrest A P M (1974) Steroid metabolism by human normal thyroid, nodular goitre and thyroid cancer. Br J Cancer 2Q.; 284-287. 29. Miller W R, Shivas A A and Forrest A P M (1976) Steroid interconversions by metastatic deposits of a human bronchogenic carcinoma. Clinical Oncology 2; 127-130.SEQTIQN C - URINARY STEROIDS IN PATIENTS WITH BREAST DISEASE 30. Miller W R, Hamilton T, Champion H R, Wallace I W J, Forrest A P M, Prescott R J, Cameron E H D and Griffiths K (1975) Urinary aetiocholanolone in patients with early breast cancer from South East Scotland and South Wales. Br J Cancer 828:619-627. 31. Prescott R J, Miller W R and Hamilton T (1978) Urinary aetiocholanolone and prognosis in early carcinoma of the breast. J Surgical Oncology 10:847-851.SECTION D - COMPOSITION OF BREAST FLUIDS 32. Miller W R, Humeniuk V and Kelly R W (1980) Dehydroepiandrosterone sulphate in breast secretions. J Steroid Biochem 18:145-1 51. 33. Miller W R, Humeniuk V and Forrest A P M (1981) Factors affecting dehydroepiandrosterone sulphate levels in human breast secretions. Breast Cancer Research & Treatment 1;267- 272. 34. Yap P L, Miller W R, Humeniuk V, Pryde E A D, Mirtle C L and McClelland D B L (1981) Milk protein concentrations in the mammary sections of non-lactating women. J Reprod Immunol 2; 49-58. 35. Miller W R, Roberts M M, Creel R J, Yap P L, Kelly R W and Forrest A P M (1982) Androgen conjugates in human breast cyst fluids. J.Nat. Can. Inst. 1055-1058. 36. Miller W R and Forrest A P M (1 983) Androgen conjugates in human breast secretions and cyst fluids. In "Endocrinology of Cystic Breast Disease" Ed. A Angeli et al. Published by Raven Press, New York pp. 77-84. 37. Miller W R, Dixon J M, Scott W N and Forrest A P M (1983) Classification of human breast cysts according to electrolyte and androgen conjugate composition. Clin Oncology 9;227-232. 38. Dixon J M, Miller W R, Scott W N and Forrest A P M (1983) The morphological basis of human breast cyst populations. Br J Surg 70:604-606. 39. Dixon J M and Miller W R (1984) Human Breast cystic disease. Breast News 1;6—9. 40. Dixon J M, Scott W N and Miller W R (1985) Natural history of cystic disease: the importance of cyst type. Br J Surg 22.5190-1 92. 41. Dixon J M, Lumsden A B and Miller W R (1 985) The relationship of cyst type to risk factors for breast cancer and the subsequent development of breast cancer in patients with breast cystic disease. Europ J Cancer 21:1Q47-1050. 42. Dixon J M and Miller VI R (1984) The pH of human breast cyst fluids. Clinical Oncology 10:221-224. 43. Yap P C, Miller W R, Roberts M M, Creel R J, Freedman B, Pryde E A D and McClelland D B L (1984) Protein concentrations in fluid from gross cystic disease of the breast. Clinical Oncology 1 0:35-43. 44. Miller W R and Dixon J M (1986) Hormonal correlates of apocrine secretion in the breast. Annals of the New York Academy of Science 464:275-287. 45. Miller W R and Dawes J (1985) Platelet-associated proteins in human breast cyst fluids. Clin Chim Acta 192:37-42. 46. Dixon J M, Scott W N and Miller W R (1 985) An analysis of the content and morphology of human breast microcysts. Europ J of Surg Oncol H; 151-154.SECTION E = MARKERS OF TUMOUR BEHAVIOUR 47. Hawkins R A, Hill A, Freedman B, Killen E, Buchan P, Miller W R and Forrest A P M (1977) Oestrogen receptor activity and endocrine status in DMBA induced rat mammary tumours. European J Cancer 13.5223-228. 48. Hawkins R A, Hill A, Freedman B, Killen E and Miller W R (1978) Oestrogen receptor activity in transplantable ovary independent mammary tumours of the rat. Europ J Cancer 14;83-90. 49. Hawkins R A, Tesdale A, Freedman B, Telford J and Miller W R (1981) Progestogen and oestrogen receptor activity in ovary dependent and ovary independent tumours of the rat. Europ J Cancer 5.558 5-587- 50. Mason R C, Steele R J C, Hawkins R A, Miller W R and Forrest A P M (1982) Cellularity and the quantification of oestrogen receptors. Breast Cancer Treatment and Research 2.5239-242. 51. Miller W R, Telford J and Hawkins R A (1 983) Binding of 3h methyltrienolone (R1881) by human breast cancers. Europ J Cancer (Clin Oncology) 12.5 1473-1478. 52. Miller W R, Telford J, Dixon J M and Hawkins R A (1 985) Androgen receptor activity in human breast cancer and its relationship with oestrogen and progestogen activity. Europ J Cancer 21;539-542. 53. Watson DMA, Kelly R W, Hawkins R A and Miller W R (1984) Prostaglandins in human mammary cancer. Br J Cancer 4Q45Q- 464. 54. Miller W R, Senbanjo R 0, Telford J and Watson DMA (1 985) Cyclic AMP binding proteins in human breast cancer. Br J Cancer 52.5531-535. 55. Miller W R, Sturgeon C M and Walker R A (1 983) Carcino embryonic antigen (CEA) in explants of human breast cancer: comparison of immuno histochemical detection and release during short-term culture. Br J Cancer 47:429-432. 56. Zangerle P F, Collette J, Hendricks J C, Miller W R and Franchimont P (1982) Milk proteins and breast cancer. In "Markers for Diagnosis and Monitoring of Human Cancer" Ed. M I Colnaghi, G I Buragge, Ghione M. Academic Press, London and New York. pp 35-49. 57. Walker R A, Hawkins R A and Miller W R (1985) Lectin binding and steroid receptors in human breast carcinomas. J Pathol 147; 103-106.SECTION F - DIRECT EFFECTS OF POLYPEPTIDES .ON BREAST CANCER CELLS 58. Miller W R, Scott W N, Morris R, Fraser H M and Sharpe R M (1 985) Growth of human breast cancer cells inhibited by a luteinizing hormone-releasing hormone agonist. Nature 311;231-233. 59. Miller W R, Scott W N, Morris R, Fraser H M and Sharpe R M (1986) Direct effects of LHRH and agonists on human breast cancer cells. "Neuroendocrine Molecular Biology". Ed. G Fink, A J Harmar, K W McKerns. Plenum Press: New York and London. Pp.475-488.SECTION G - REVIEWS 60. Forrest A P M and Miller W R (1985) Hormones and female breast cancer: clinical relevance. In "Accomplishments in Cancer Research" General Motors Publication Ed J G Fortner and J E Rhoads.Pub. J B Lippincott Co. Philadelphia pp 134- 151 . 61. Miller W R and Anderson, T A Oestrogens, progestogens and the breast. In "The Menopause". Eds M I Whitehead and J Studd. Pub.Blackwell Scientific Press (in press)

Measurement of τ decays involving η mesons

complete author list: Artuso M.; Goldberg M.; Horwitz N.; Kennett R.; Moneti G.; Muheim F.; Playfer S.; Rozen Y.; Rubin P.; Stone S.; Thulasidas M.; Yao W.; Zhu G.; Barnes A.; Bartelt J.; Csorna S.; Egyed Z.; Jain V.; Sheldon P.; Akerib D.; Barish B.; Chadha M.; Cowen D.; Eigen G.; Miller J.; Urheim J.; Weinstein A.; Acosta D.; Masek G.; Ong B.; Paar H.; Sivertz M.; Bean A.; Gronberg J.; Kutschke R.; Menary S.; Morrison R.; Nelson H.; Richman J.; Tajima H.; Schmidt D.; Sperka D.; Witherell M.; Procario M.; Yang S.; Daoudi M.; Ford W.; Johnson D.; Lingel K.; Lohner M.; Rankin P.; Smith J.; Alexander J.; Bebek C.; Berkelman K.; Besson D.; Browder T.; Cassel D.; Coffman D.; Drell P.; Ehrlich R.; Galik R.; Garcia-Sciveres M.; Geiser B.; Gittelman B.; Gray S.; Hartill D.; Heltsley B.; Honscheid K.; Jones C.; Kandaswamy J.; Katayama N.; Kim P.; Kreinick D.; Ludwig G.; Masui J.; Mevissen J.; Mistry N.; Ng C.; Nordberg E.; Ogrady C.; Patterson J.; Peterson D.; Riley D.; Sapper M.; Selen M.; Worden H.; Worris M.; Würthwein F.; Avery P.; Freyberger A.; Rodriguez J.; Stephens R.; Yelton J.; Cinabro D.; Henderson S.; Kinoshita K.; Liu T.; Saulnier M.; Wilson R.; Yamamoto H.; Sadoff A.; Ammar R.; Ball S.; Baringer P.; Coppage D.; Copty N.; Davis R.; Hancock N.; Kelly M.; Kwak N.; Lam H.; Kubota Y.; Lattery M.; Nelson J.; Patton S.; Perticone D.; Poling R.; Savinov V.; Schrenk S.; Wang R.; Alam M.; Kim I.; Nemati B.; Oneill J.; Romero V.; Severini H.; Sun C.; Wang P.; Zoeller M.; Crawford G.; Fulton R.; Gan K.; Kagan H.; Kass R.; Lee J.; Malchow R.; Morrow F.; Sung M.; White C.; Whitmore J.; Wilson P.; Butler F.; Fu X.; Kalbfleisch G.; Lambrecht M.; Ross W.; Skubic P.; Snow J.; Wang P.; Bortoletto D.; Brown D.; Dominick J.; McIlwain R.; Miao T.; Miller D.; Modesitt M.; Schaffner S.; Shibata E.; Shipsey I.; Battle M.; Ernst J.; Kroha H.; Roberts S.; Sparks K.; Thorndike E.; Wang C.; Sanghera S.; Skwarnicki T.; Stroynowski R.; Artuso M.</p